For a case of recurrent aboion, most common parental chromosomal abnormalities associated is ?

Parental Chromosomal Abnormalities account for only 2 to 4 percent of RPL cases and in such cases karyotyping of both parents is considered essential. Of abnormalities, reciprocal translocations are most common and followed by robesonian translocations In the choices given above, the best answer is robesonian translocation Robesonian Translocations. These involve only acrocentric chromosomes, which are chromosomes 13, 14, 15, 21, and 22.Robesonian translocations are found in 1 in 1000 individuals. The incidence of abnormal offspring approximates 15 percent if a robesonian translocation is carried by the mother and 2 percent if carried by the father. Robesonian translocations are not a major cause of miscarriage and are found in fewer than 5 percent of couples with recurrent pregnancy loss. When a fetus or child is found to have a translocation trisomy, both parents should be offered karyotype analysis. If neither parent is a carrier, the recurrence risk is extremely low.