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Physiology Regulation of Respiration 9e120ae1

Hyperinflation of lungs is prevented by-

A
Hering Breuer reflex
B
Irritation reflex
C
Cushing reflex
D
Bainbridge reflex
High-Yield Explanation
Ans. is 'a' i.e., Hering Breuer reflexo Hering-Breuer inflation reflex : This reflex is mediated by pulmonary stretch receptors in w hich inflation of lungs above a particular volume results in reflex inhibition of inspiration and initiation of expiration. The reflex tends to limit the tidal volume while increasing the respiratory frequency.o Hering-Breuer deflation reflex : - Rapid deflation of lungs tends to initiate prolonged inspiration, i.e., reflex hyperpnea in response to deflation.NameLocationStimulationAfferentResponseBaroreceptorsArterialCarotid sinus-9th nerve Aortic arch-1 Oth nerve|BPAff.-9th 10th NTS Eff.-Buffer n.|Sympathetic vasoconstrictor tone |Sympathetic discharge to heart |Parasympathetic discharge to heartCentral venous pressure receptorLt. atrium Pulmonary veins wall of great veins (SVC/Jugular veins) 10th nerve ChemoreceptorsCentralMedullaCO; HyperventilationPeripheralCarotid & Aortic bodyHemorrhage Hypoxia Hypercapnia acidosisStimulates VMCPeripheral Vasoconstriction |CO,|THR,|BPBainbridge ReflexesRt. atrium/vena cavaeRapid infusion of blood'saline (atrial distension) reflex tachycardiaBezold-Jariseh/ Coronary ChemoreflexLt. VentricleInj. of 5-HT, Veratrum Capsaicin, Nicotine in coronary artery Apnea, |-BP, |HR Tachypnea later onJ. Reflex/Pulmonary chemoreflexJuxtacapillary in walls of alveoli. C-fibresHyperinflation of lung (normal inspiration) -do-Cushing ReflexVMC|ICT | in blood supply ot VMC | systemic BP reflex | in HRHering Breuer Reflex-Inflation -DeflationAirway SM cellsSteady Lung inflation Mark deflation of lung| expiration | expiration

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