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Pharmacology A.N.S. 9d0b5adc

Which of the following alpha-blocker drug is used in BPH without producing hypotension?

A
Doxazosin
B
Phentolamine
C
Tamsulosin
D
Terazosin
High-Yield Explanation
Ans. C. Tamsulosina. Tamsulosin, Silodosinb. Higher affinity for a1A/1D receptors (found on prostate smooth muscle) than for a1B subtype (found on vascular smooth muscle)c. Minimal effect on blood pressured. High oral bioavailabilitye. Silodosin is a newer a1A blocker used in BPH.

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