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Pharmacology Hematology and CVS 9c7fb109

Drugs that have been found to be useful in compensated hea failure include all of the following except:

A
Na+ K+ ATPase inhibitors
B
Aldosterone antagonists
C
BNP analogue
D
Beta receptor antagonists
High-Yield Explanation
BNP analogue (Nesiritide) are used in acute cardiac failure not used in chronic therapy. Compensated hea failure (Chronic CHF): Management: Digitalis (Na+ - K+ ATPase inhibitor) - Inhibit Na+/K+ ATPase--> positive inotropic action. It does not acts as chronotropic agent so no increase in workload on hea and useful in chronic conditions. Aldosterone antagonist: Decreases morbidity/moality. Used to prevent cardiac remodelling along with ACE inhibitors and ARBs. b blockers: These drugs can precipitate acute decompensation of cardiac function but are used in chronic CHF as these decrease moality by reversing LVH.

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