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Ophthalmology General 9c4cc831

Retinoblastoma –

A
Is inherited in 50% of cases
B
Is caused by deletion of 11q14
C
Rosettes suggest good prognosis
D
Causes death in 60% of sufferers in the UK
High-Yield Explanation
Rosettes are feature of well differentiated retinoblastoma, therefore suggest the good prognosis. Hereditary retinoblastoma accounts for 40% of cases and the gene is located at 13q14 chromosome. Prognosis is fair with 70-85% survival rate if the eyeball is enucleated before the occurrence of extra ocular extension.

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