Which of the following is not true regarding Chlamydia?

Ans. (b) Elementary body is metabolically active Reproductive Cycle of Chlamydiae Elementary body (EB) Stable spherical form, metabolically inactive - Extracellular phase Infectious form 200 - 300 nm diameter Rigid trilaminar cell wall Electron dense nucleoid (contains DNA) DNA = RNA Attach to surface of susceptible epithelial cell near base of microvilli by adhesins (e.g. major outer membrane protein); receptors (heparin sulfate like proteoglycans in case of C. trachomatis) | Engulfment of EB into host cell either by endocytosis into clathrin-coated pits or pinocytosis into non-coated pits. Lysosomal fusion is inhibited by unknown mechanism, so EB form of chlamydiae is protected under membrane bound environment. | Reorganisation of EB by spheroplast-like transformation/loss of cross-linking of EB membrane proteins. Reticulate body (Initial body form) - Pleomorphic stage Intracellular form Growing and replicative form 500-1000 nm size No electron dense nucleoid RNA > DNA Within membrane bound vacoule RB divides by binary fission repeatedly to form EB. |Cytoplasmic inclusion bodies form (EB filled vacoule) |This EB liberate from host cell to infect new cells.