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Pathology NEET 2019 9b9dafd3

Hemolysis is predominantly intravascular in which of the following conditions?

A
Warm-type autoimmune hemolytic anemia
B
PNH
C
Cold-type autoimmune hemolytic anemia
D
Hereditary spherocytosis
High-Yield Explanation
- Intravascular hemolysis (predominant) is seen in: Paroxysmal nocturnal hemoglobinuria (PNH) G6PD deficiency Paroxysmal cold hemoglobinuria (Cold hemolysin disease) - Extravascular hemolysis (predominant) is seen in: Hereditary spherocytosis Warm-type autoimmune hemolytic anemia Cold agglutinin disease (Cold-type AIHA) Sickle cell disease

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