A 9-year-old boy is brought with history of decreased urine output, cola colored urine and swelling of the face and hands of 2 days duration. He is hypertensive, has a puffy face and pitting edema of the lower limbs. He has history of skin lesions 4 weeks earlier. A diagnosis of post streptococcal glomerulonephritis is made. If an antibiotic is to be used to limit the spread of the nephritogenic organisms, the drug of choice is?
High-Yield Explanation
b. Penicillin(Ref: Nelson 20/e p 2500-2501, Ghai 8/e p 474-477)Treatment of PSGNManagement is directed at treating the acute effects of renal insufficiency and hypertensionAlthough a 10 day course of systemic antibiotic therapy with penicillin is recommended to limit the spread of the nephritogenic organisms, antibiotic therapy does not affect the natural history of PSGNTreatment of hypertension: Calcium channel antagonists, vasodilators, or angiotensin-converting enzyme inhibitors.