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Pathology Endocrinology 9b4fda50

Most common thyroid Cancer is

A
Papillary carcinoma
B
Follicular carcinoma
C
Medullary carcinoma
D
Anaplastic carcinoma
High-Yield Explanation
Papillary carcinoma of thyroid: - constitutes >85% of all thyroid carcinoma - occurs due to mutation of genes encoding: *RET gene *NTRK1 receptor tyrosine kinases *BRAF gene These tumours may be solitary or multivocal. On microscopy: - branching papillae with fibrovascular stalk lined by cuboidal epithelium - nuclei of cells are optically clear with dispersed chromatin and has Orphan Annie eye nuclei (Ref : ROBBINS Text book of pathology) REF IMG

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