Pharmacology Anesthesia 9b1d56d1

Which of the following drug do not cross the blood-brain barrier?

Diacetyl monoxime

Obidoximine

Physostigmine

Neostigmine

High-Yield Explanation

Neostigmine being a quaternary ammonium compound and highly polar cannot cross BBB.Pralidoxime which is used in OP poisoning also can&;t cross the BBB.Ref: Katzung 11th ed.Pg 121

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Which of the following drug do not cross the blood-brain barrier?

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