Which of the following is not a feature of drug dependence

A definite diagnosis of dependence should usually be made only if at least three of the following have been experienced or exhibited at some time during the previous year: 1. A strong desire or sense of compulsion to take the substance. 2. Difficulties in controlling the substance-taking behaviour in terms of its onset, termination, or levels of use. 3. A physiological withdrawal state when the substance use has ceased or reduced, as evidenced by the characteristic withdrawal syndrome for the substance; or use of the same (or a closely related) substance with the intention of relieving or avoiding withdrawal symptoms. 4. Evidence of tolerance, such that increased doses of the psychoactive substance are required in order to achieve effects originally produced by lower doses. 5. Progressive neglect of alternative pleasures or interests because of psychoactive substance use, the increased amount of time necessary to obtain or take the substance or to recover from its effects. 6. Persisting with substance use despite clear evidence of ovely harmful consequences, such as harm to the liver through excessive drinking, depressive mood states consequent to periods of heavy substance use, or drug-related impairment of cognitive functioning; effos should be made to determine that the user was actually, or could be expected to be, aware of the nature and extent of the harm. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no. 34