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Pharmacology G.I.T 9b03a779

Drug useful in hepatic encephalopathy is:

A
Magnesium sulphate
B
Lactulose
C
Bisacodyl
D
Biphosphonates
High-Yield Explanation
Ans. (B) Lactulose(Ref: KDT 8th/e p725)Lactulose is a laxative that acts by conversion to short chain fatty acids in the colon.These fatty acids result in decrease in pH of intestinal juice.At low pH, ammonia becomes ionized (NH4+ ) and thus cannot be absorbed.

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