Which of the following is the most common cause of clinically significant consumptive coagulopathy?
High-Yield Explanation
One of the most common causes of clinically significant consumptive coagulopathy in obstetrics is placental abruption. Major mechanism of consumption coagulopathy are Disseminated intravascular coagulation (DIC) and to a lesser degree retroplacental bleeding. It is associated with hypofibrinogenemia (less than 150mg/dl), raised D dimer and fibrin degradation products, and low level of coagulation factors factor V, VIII.