Full 2L QBank
Pathology General 9a70829a

Steroid resistant nephritic syndrome is caused by mutation in which of the following?

A
Nephrin
B
Alpha-actinin-4
C
Podocin
D
Transient Receptor Potential 6
High-Yield Explanation
A mutation in the Nephrin (NPHS1) gene causes a hereditary form of congenital nephrotic syndrome with minimal change glomerular morphology whereas mutations in NPHS2 encoding for podocin results in steroid resistant nephrotic syndrome. Ref: Robbins 7Th Ed Page 981, 983.

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now