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Physiology General 9a368df4

All are true about neurotrophins except ?

A
Help integrity of postsynaptic neurons
B
TrK B is associated with brain derived neurotrophic factor
C
Helps in growth of cholinergic neurons in basal forebrain
D
Always transpoed antegrade along the axon
High-Yield Explanation
Ans. is 'd' i.e., Always transpoed antegrade along the axon NeurotrophinsThis name is given to a group of proteins necessary for the survival and growth of neurons.Some of them are synthesized by extraneuronal structures innervated by the neurons, e.g. skeletal muscle innervated by alpha-motor neurons and tissue innervated by autonomic neurons.Many are produced by astrocytes.From the non-neural tissues, neurotrophins are taken up by endocytosis at the nerve terminal and transpoed to the soma by axonal retrograde transpo mechanism.

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