In graft rejection, type of HLA involved is?

In transplantation immunology, the major impact in graft loss comes from the effects of HLA-B and HLA-DR antigens The histocompatibility antigens (human leukocyte antigens - HLA) are cell surface antigens that induce a response leading to rejection of allografts The principal physiologic function of the cell surface histocompatibility molecules is the bound peptide fragments foreign proteins for presentation to antigen-specific T cells. The histocompatibility antigens are encoded by a closely linked multiallelic cluster of genes: Mix histocompatibility complex (MHC) or Human leukocyte antigens complex (HLA complex) HLA complex of genes is located on the short arm of chromosome 6. It consists of three separate clusters of genes: HLA Complex (MHC complex)