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Pathology Urinary tract 99891f49

Collapsing glomerulopathy, features are-

A
Tuft necrosis
B
Mesangiolysis
C
Parietal epithelial proliferation
D
Hyperophy and necrosis of visceral epithelium
High-Yield Explanation
Besides the lesions of focal and segmental scarring, a variant of FSGS, collapsing glomerulopathy, has been described in HIV patients. It is a segmental or global glomerular collapse of the tuft along with the presence of hyperpasia and hyperophy of podocytes producing a pseudo-crescent and a rapid decline in renal function. Ref: Harsh Mohan textbook of pathology 6th edition page674

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