A 40 year male presented with massive splenomegaly. There was mild hepatic enlargement also. Peripheral blood film shows cells with hair like projections; which are positive for CD 25 and CD 103 and negative for CD 23. The likely diagnosis is a :
High-Yield Explanation
Peripheral B - cell neoplasm Hairy cells on peripheral blood smear and CD 103 positivity are diagnostic of hairy cell leukemia which is a peripheral B cell neoplasm.