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Medicine General 99586cdf

A 20 yrs adult presents with severe hypoplastic anemia. What is most effective treatment :

A
a-interferon
B
IL-2
C
ATG therapy
D
Bone marrow transplantation
High-Yield Explanation
Answer is D (Bone marrow transplantation) `Bone marrow transplantation is the best therapy for the young patient with a fully histocompatible sibling donor.' The curative treatment for young (<20 year-old) patients with severe idiopathic aplastic anemia is allogenic bone marrow transplantation if there is an available donor. Those with a compatible sibling donor should proceed to transplantation as soon as possible.

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