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Pathology General 994ef8fe

Adrenoleukodystrophy is?

A
AD
B
AR
C
X linked dominant
D
X linked recessive
High-Yield Explanation
Ans. is 'd' i.e., X Linked recessiveAdrenoleukodystrophv:Adrenoleukodystrophy is an X-linked recessive disease associated with mutations in a member of the ATP-binding cassette transpoer family of proteins (ABCD1), which is involved in the transpo of molecules into the peroxisome.In the typical form of the disease, young males present with behavioral changes and adrenal insufficiency.The disease is characterized by the inabil- ity to catabolize very-long-chain fatty acids (VLCFAs) within peroxisomes, resulting in elevated levels of VLCFAs in serum.

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