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Pathology Small and Large Intestines 99491e4b

Gluten sensitivity is associated with?

A
Celiac disease
B
Tropicalsprue
C
Ulcerative colitis
D
Irritable bowel syndrome
High-Yield Explanation
Ans. is 'a' i.e., Celiac disease o Celiac disease is a chronic malabsorption syndrome due to intestinal hypersensitivity to gliadin, component of gluten in wheat, oat, barely and rye.o Strongest association of coeliac disease is seen with HLA-DQ2 followed by H2A-DQ8. Other HLA types (B8, DR3 and DR7) have also been associatedo Coeliac disease may be associated with dermatitis herpetiformis.

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