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Pharmacology C.N.S 9942c9c4

Which drug is given in the pain due to diabetic neuropathy?

A
Lamotrigine
B
Na valproate
C
Gabapentin
D
Morphine
High-Yield Explanation
Ans. is 'c' i.e., Gabapentin Gabapentin* This is lipophilic GABA derivatve.* Gabapentin enhances GABA release but itself does not act as a agonist at the GABAA receptor.* It crosses to the brain and enhances GABA release but does not act as agonist at GABAA receptor.* Gabapentin is considered to be a first line drug for pain due to diabetic neuropathy and postherpetic neuralgia.Usesi) GTCS and partial seizuresii) Postherpetic neuralgiaiii) Pain due to diabetic neuropathyiv) Prophalaxis of migraine

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