Full 2L QBank
Biochemistry Enzymes 9933ad20

Which of the following is not secreted as zymogen?

A
Pepsin
B
Trypsin
C
Amylase
D
Colipase
High-Yield Explanation
The binding of co-lipase to the triacylglycerol molecules at the oil-water interface is obligatory for the action of lipase. The co-lipase is secreted by the pancreas as an inactive zymogen (molecular weight 11,000). It is activated by trypsin. The major enzyme present in gastric juice is pepsin. Its action on dietary proteins is indicated in Chapter 14. One of the functions of HCl is to activate the zymogen pepsinogen to pepsin by paial proteolysis. In addition, the HCl helps in the absorption of iron and calcium. The gastric juice also contains a glycoprotein required for the absorption of B12, the Castle&;s intrinsic factorRef: DM Vasudevan, page no: 310

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