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Medicine General 98c94db9

Splenectomy is contraindicated in which of the following haemolytic anemia:

A
Stomatocytosis
B
Elliptocytosis
C
Sickle cell disease
D
All of the above
High-Yield Explanation
Stomatocytosis: This rare condition with autosomal dominant inheritance draws its name (mouth-like cells) from the fact that the normally round-shaped central pallor of red cells is replaced by a linear-shaped central pallor. Hemolysis is usually relatively mild. Splenectomy is contraindicated as it has been followed in a majority of cases by severe thromboembolic complications. Ref: Harrison's principle of internal medicine 17th Edition, Chapter 101.

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