A patient is brought to the emergency depament following a road traffic accident. MRI shows injury to corpus striatum. This patient is MOST likely to suffer from:
High-Yield Explanation
Clinicopathologic Correlations of Extrapyramidal Movement Disorders: Symptoms Principal Location of Morbid Anatomy Unilateral plastic rigidity with rest tremor (Parkinson disease) Contralateral substantia nigra Unilatral hemiballismus and hemichorea Contralateral subthalamic nucleus of Luys or luysial-pallidal connections Chronic chorea of Huntington type Caudate nucleus and putamen Athetosis and dystonia Contralateral striatum (pathology of dystonia musculorum deformans unknown) Cerebellar incoordination, intention tremor, and hypotonia Ipsilateral cerebellar hemisphere; ipsilateral middle or inferior cerebellar peduncle; brachium conjunctivum (ipsilateral if below decussation, contralateral if above) Decerebrate rigidity, i.e., extension of arms and legs, opisthotonos Usually bilateral in tegmentum of upper brainstem at level of red nucleus or between red and vestibular nuclei Palatal and facial myoclonus (rhythmic) Ipsilateral central tegmental tract with denervation of inferior olivary nucleus and nucleus ambiguus Diffuse myoclonus Neuronal degeneration, usually diffuse or predominating in cerebral or cerebellar coex and dentate nuclei Ref: Ropper A.H., Samuels M.A. (2009). Chapter 4. Abnormalities of Movement and Posture Caused by Disease of the Basal Ganglia. In A.H. Ropper, M.A. Samuels (Eds), Adams and Victor's Principles of Neurology, 9e.