Full 2L QBank
Dental Eczema and related disorders 982f6d0c

A 25 year old male presents with recurrent lip edema to the OPD. On performing lab investigations, it revealed |C4, |C1-INH levels, |C1-INH function, normal C1q levels. What is the most probable diagnosis?

A
Hereditary angioedema Type 1
B
Hereditary angioedema Type 2
C
Acquired angioedema Type 1
D
Acquired angioedema Type 2
High-Yield Explanation
Hereditary angioedema(HAE) Disorder characterized by recurrent episodes of severe swelling (angioedema). 3 main types of HAE. Type I and II are caused by a mutation in the SERPING1 gene that makes the C1 inhibitor protein while type III is often due to a mutation of the factor KhII gene. This results in increased amounts of bradykinin which promotes swelling. Distinguishing b/w HAE & AAE( Acquired angioedema): C1q levels normal-HAE C1q levels low-AAE Type 1 HAE-Low C1-INH level & low C4 level Type 2 HAE- Normal or elevated C1-INH level & low C4 level. Function of C1-INH is reduced in both type 1 & 2 HAE.

Related Dental MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now