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Pharmacology General 98227d65

Which antianginal drug can be safely used with drugs used for treatment of erectile dysfunction?

A
Nitrates
B
Calcium channel blockers
C
pFOX inhibitor
D
Potassium channel opener
High-Yield Explanation
Ans. is'c'i.e., pFOX inhibitor The metabolic modulators (eg, trimetazidine) are known as pFOX inhibitors because they paially inhibit fatty acid oxidation pathway in myocardium.Antianginal action of trimetazidine is independent of any blood pressure reduction.It can be effectively used as an antianginal drug in the CAD patients with erectile dysfunction in the place of nitrates to allow free use of sildenafil and similar agents.

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