Anatomy General anatomy 98186f26 Resistance to Zidovudine develops due to A Mutation at reverse transcriptase B Increased efflux of the drug from inside the cell C Increased metabolism of drug D Decreased Zidovudine 5 triphosphate formation High-Yield Explanation Zidovudine is a nucleoside reverse transcriptase inhibitors which is a viral enzyme .HIV undergoes mutations in this enzyme to become resistant to NIs Refer :KDT 6/e p770