Which of the following is false about scleroderma?
High-Yield Explanation
Ans. D. Female preponderance of 9:1Scleroderma or Systemic Sclerosis is an autoimmune rheumatic disease in which there is a 4:1 female predominance. A wide spectrum of clinical features are seen in Scleroderma:* Severe pruritus* Initially, scleroderma patients experience puffiness and non-pitting edema of fingers.* The skin later becomes indurated, thickened, and fixed to underlying structures resulting in sclerodactyly.* Vasospasm and Digital ulceration* Around 90% of patients suffering from scleroderma, have dysphagia, and GERD at the level of esophagus.* Mask like facies is seen due to the waxy nature of skin and lack of wrinkles.Typical facial features: note the expressionless facies, mat-like telangiectases, microstomia, perioral furrowing and beak-like nose.Digital UlcerationAdvanced-stage sclerodactyly with contractures and vasculopathic ulcers over the bony prominences