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Microbiology General 9777f2c1

EBV causes: March 2013

A
Infectious mononucleosis
B
Nasopharyngeal carcinoma
C
Glandular fever
D
All of the above
High-Yield Explanation
Ans. D i.e. All of the above Epstein-Barr virus (EBV)/ Human herpesvirus 4 (HHV-4) It is a virus of the herpes family, and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis (glandular fever). It is also associated with paicular forms of cancer, such as Hodgkin's lymphoma, Burkitt's lymphoma, nasopharyngeal carcinoma, and conditions associated with human immunodeficiency virus (HIV) such as hairy leukoplakia and central nervous system lymphomas. There is evidence that infection with the virus is associated with a higher risk of ceain autoimmune diseases, especially dermatomyositis, systemic lupus erythematosus, rheumatoid ahritis, Sjogren's syndrome, and multiple sclerosis. Infection with EBV occurs by the oral transfer of saliva and genital secretions.

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