Hepatitis B remains in latent period for a long time but still there is increased risk of HCC, what is the cause of this transformation?

ANS. DLet us analyze this question by looking at each option.Option A is a correct statement, but inability to induce inflammation is not the cause for transformation into hepatocellular carcinoma.Option B is not definitely the cause for HCC as elevated transaminases does not have anything to do with HCC.Option C is not correct as in latent period, there is no proliferation of hepatocytes.Option D is the answer and integration of viral DNA with host DNA causes transformation into HCC.