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Pathology General 972775ac

Eosinophilia in necrosed tissue is due to

A
Coagulation of proteins
B
Denaturation of enzymes
C
Denaturation of protein
D
Mitochondrial damage
High-Yield Explanation
Ans. is 'c' i.e., Denaturation of protein Necrotic cells show increased eosinophilia in hematoxylin and eosin (H & E) stains. It is due to - Loss of cytoplasmic RNA (or ribonucleoprotein/RNP) which binds the blue dye, hematoxylin. Denatured cytoplasmic proteins which bind the red dye, eosin.

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