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Physiology Cardiovascular system 969739c1

All of the following factors normally increase the length of the ventricular cardiac muscle fibers except

A
Increased venous tone
B
Increased total blood volume
C
Increased negative intrathoracic pressure
D
Lying to standing change in posture
High-Yield Explanation
Heteromeric regulation of stroke volume includes factors that regulate cardiac output as a result of changes in cardiac muscle length. End-diastolic volume has a role increasing the length of cardiac muscle fibres. .Venous return and ventricular filling are the factors affecting EDV. Venous return is affected by skeletal muscle pump, venous tone, negative intrathoracic pressure due to its suckinv effect, lying down posture than standing posture, increased blood volume. Ref: Textbook of medical physiology by N Geetha, 2nd edition, page no. 169,170

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