Pharmacology Other topics and Adverse effects 968f94f1 Which of the following adverse effects is most likely to occur with sulfonamides? A Neurologic effects including headache, dizziness, and lethaargy B Hematuria C Fanconi's anemia D Skin reactions High-Yield Explanation (Ref: KDT 6/e p684) Rash is the most common adverse effect seen with the use of sulfonamides.