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Pathology General 960abf30

Wilson's disease is caused by mutation in:

A
ATP7A
B
ATP7B
C
HFE
D
HAMP
High-Yield Explanation
Wilson disease is an autosomal recessive disorder caused by mutation of the ATP7B gene, resulting in impaired copper excretion into bile and a failure to incorporate copper into ceruloplasmin. Ref: Robbins 8th edition Chapter 18.

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