Cell organelle affected in Wolman’s Disease is
High-Yield Explanation
Characteristics of Lysosomes
Discovered by Christian de Duve
Contains acid hydrolases,acid lipases,collagenase
ATP-dependent proton pumps in the membrane maintain an acidic environment (pH 4.0–5.0)
Lysosomal Diseases
Tay-Sachs disease
Hexosamidase A
Gaucher’s disease
Beta galactocerebrosidase
I-cell disease
Absent mannose-6-phosphate tag