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Microbiology Parasitology 9590147c

Calabar swelling is due to -

A
Hypersensitivity to adult worm of Loa-Loa
B
Hypersensitivity to larva of Loa-Loa
C
Hypersensitivity to adult worm of oncocerca
D
Hypersensitivity to larva of oncerca
High-Yield Explanation
Ans. is 'a' i.e., Hypersensitivity to adult worm of Loa-Loa [Ref: Chatterjee 12thIe p. 202}Loiasis* Loiasis is caused by L. Loa (the African eye worm)* Habitat of adult worms is subcutaneous connective tissue of man; often in the sub-conjuctival tissue of the eye.* The worm passes its life cycle in two hosts :# Man# Chrysops (Mango or deer flies)* It causes a characteristic subcutaneous swelling called Calabar (fugitive) swelling. It is due to hypersensitivity reaction to adult worm.

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