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Pharmacology Hematology 9588a5f3

What is the mode of action of warfarin?

A
Factor Xa inhibitor
B
Vitamin K antagonist
C
Activates antithrombin III
D
Activates factor IX
High-Yield Explanation
Ref: KD Tripathi, 7th ed. pg. 620, 621* Warfarin and its congeners act as anticoagulants only in vivo (body), NOT in vitro (lab).* It acts by inhibiting Vitamin K. Due to overdose, hematuria is the first manifestation noted.* Dose monitoring is done by INR* Antidote of warfarin overdose: Vitamin K

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