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Pharmacology Cardiovascular system 9550e307

All of the following statements about clonidine are true EXCEPT

A
It is an alpha adrenergic agonist
B
It can cause dry mouth as an adverse effect
C
Prazosin completely antagonizes its action
D
It inhibits sympathetic outflow.
High-Yield Explanation
Clonidine is a central sympatholytic. It is an agonist to alpha2 receptors. But prazosin is a selective alpha1 blocker selective alpha 2 blocker is yohimbine Clonidine can cause dryness of mouth, nose, and eyes due to central sympatholytic action. (REF. ESSENTIALS OF MEDICAL PHARMACOLOGY K.D TRIPATHI-6th edition. Page No.545,546)

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