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Pathology Miscellaneous 95307806

Barr body is found in which phase of cell cycle?

A
Interphase
B
Metaphase
C
G1 phase
D
Telophase
High-Yield Explanation
Barr body, or X chromatin The inactive X appears in the interphase nucleus as a darkly staining small mass adjacent to the nuclear membrane Molecular basis of X inactivation involves a unique gene called XIST, XIST codes for long noncoding RNA that is retained in the nucleus, where it "coats" the X chromosome that it is transcribed from and initiates a gene-silencing process by modification of chromatin and DNA methylation.

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