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General Medicine General 95259113

An infant with a history of delayed separation of umbilical cord now presents with recurrent pneumonia. The total count is 20,000/ml. Which of the following genetic defects is most likely present?

A
Low levels of NADPH oxidase and negative DHR test
B
Mutation of Bruton tyrosine kinase gene
C
Excessive IgM with reduced IgG and IgA
D
Reduced phagocyte surface expression of Sialyl-Lewis x
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