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Pharmacology Miscellaneous (Pharmacology) 950db640

Which one of the following is FALSE about Ticlopidine?

A
Inhibits platelet function by inducing a thrombasthenia like state
B
Stimulates platelet aggregation and clot retraction
C
Prolongs the bleeding time
D
Directly interacts with platelet membrane glycoprotein IIb/IIIa receptors
High-Yield Explanation
(B) Stimulates platelet aggregation and clot retraction# Aspirin, Ticlopidine, Dipyridamole are antiplatelet drugs.> Ticlopidine interacts with platelet membrane GP llb/llla & alters fibrinogen binding to platelets.> Ticlopidine inhibits platelet aggregation & clot retraction. It has no effect on TXA2, but bleeding time is prolonged.

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