Misoprostol is indicated in all of the following except: September 2005, 2010

Ans. D: Menorrhagia Misoprostol is commonly used for labor induction. It causes uterine contractions and the ripening (effacement or thinning) of the cervix. Misoprostol is more effective in staing labor than other drugs used for labor induction. It is also significantly less expensive than the other commonly used agents. Misoprostol is one of the drugs used for medical aboions in lieu of surgical evacuation. The advantages of medical aboion over surgical aboion include reduced invasiveness of the procedure, lack of risks from general anesthesia (which is often used for surgical aboions), and lack of risk of secondary infeility due to scarring and intrauterine adhesions (Asherman's Syndrome). Misoprostol can also be used to dilate the cervix in preparation for a surgical aboion, paicularly in the second trimester (either alone or in combination with laminaria stents). Misoprostol is sometimes used to treat early fetal death in the absence of spontaneous miscarriage. Misoprostol is also used to prevent and treat post-paum hemorrhage, but it has more side effects and is less effective than oxytocin for this purpose.