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Pharmacology Anaesthesia 94647f07

True statement regarding Bupivacaine is

A
Used as intravenous along with lignocaine
B
More cardiotoxic than lignocaine
C
Contraindication in pregnancy
D
All of the above
High-Yield Explanation
(More cardiotoxic than Lignocaine)(326-KDT) (357-KDT6th)BUPIVACA1NE - long acting amide linked LA used for infiltration, nerve block, epidural and spinal anaesthesia of long duration* A 0.25-0.5% solution injected epidurally produces adequate analgesia without significant motor blockade. As a result it has become very popular in obstetrics (mother can actively cooperate in vaginal delivery).* ** Bupivacaine is more prone to prolong QTc interval and induce ventricular tachycardia or cardiac depression-should not be used for intravenous regional analgesia. (UP-2010)* It should not be used for Beir block (because of its cardiotoxicity)* Drug of choice for ventricular tachycardia produced by bupivacaine is bretylium

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