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Pathology Hemoglobinopathies: Sickle cell anemia 943e2171

Autosplenectomy is seen in:

A
Hereditary spherocytosis
B
Sickle cell disease
C
Thalassaemia
D
Autoimmune anemia
High-Yield Explanation
- In sickle cell anemia initially, congestive splenomegaly is seen. - Later, sickled RBC causes aerial occlusion - ischemic damage to spleen - resulting in Fibrosis of spleen / autosplenectomy.

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