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Pediatrics Demyelinating Disorders of the CNS 94106eb8

GBS in a child treatment -

A
IVIG
B
Ventilation
C
Plasmapharesis
D
All of above
High-Yield Explanation
Ans. is 'd' i.e., All of above Guillain-Barre syndrome o Auto immune disorder, o Leads to demvelination of nerve. o H/O preceding viral infection : Infectious mononucleosis (EB Virus): Measles, mumps, ECHO, coxsackie. o Campylobacter: Strongly associated with severe form acute motor axonal neuropathy (AMAN). Clinical feature o Symmetrical weakness of LMN type Ascending type, o Subjective sensory involvement. o Facial nerve palsy seen in 3 /4th of cases. o Involvement of autonomic nervous systems, (urinary retenstion, hypo or hypertension). Diagnosis o CSF - Albumino cytological dissociation (Protein is elevated in 80% of cases but cell count normal). Treatment o Self limited in majority of cases, o Intravenous immunoglobin shows good response, o Plasma pharesis - Removal of autoantibodies, o Assisted ventilation - If patient had respiratory muscle paralysis, o Physiotherapy.

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