Surgery Pancreas 93fb4f26 Most common oncogene involved in pancreatic carcinoma is: A P53 B K-RAS C APC D DCC High-Yield Explanation Ans. (b) K-RASRef: Sabiston's Textbook of Surgery, 20th ed p-1543* As per Sabiston 95% cases have K ras mutation and 90% cases have P16 mutation.