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Pathology Genetics 93f2321e

SnRNA mutation is associated with which syndrome?

A
Turner syndrome
B
Prader Willi syndrome
C
Klinefelter syndrome
D
Patau syndrome
High-Yield Explanation
Ans. is 'b' i.e., Prader Willi syndrome o The syndrome has been linked to the deletion of a region of paternal chromosome 15 that is not expressed on the maternal chromosome (Genomic impmting). This region includes a brain-specific snRNA that targets the serotonin- 2C receptor mRNA.

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