Post splenectomy sepsis is common in

Ans. is 'a' i.e. ITP; 'b' i.e. Thalassemia & 'c' i.e. Hereditary spherocytosis Schwaz writes about Postsplenectomy infections " Reason for splenectomy is the single most influential determinant of OPSI risk. Case series demonstrate that those who undergo splenectomy for hematologic disease (malignancy, myelodysplasia, or hemoglobinopathy) are far more susceptible to OPSI than patients who undergo splenectomy for trauma or iatrogenic reasons. Age is also an impoant consideration, with children 50 years being at elevated risk."