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Gynaecology & Obstetrics General 93d4dad2

Chemotherapy for dysgerminoma is:

A
Cisplatin, etoposide, bleomycin
B
Cyclophophamide, vincristine, prednisolone
C
Adriamycin, cyclophophamide, cisplatin
D
Methotrexate, oncovin, cyclophosphamide
High-Yield Explanation
Management of Dysgerminoma: • The treatment of early dysgerminoma. Surgical – including resection of the primary lesion (unilateral oophorectomy) and proper surgical dissection. • Metastatic Disease – Chemotherapy or Radiation therapy. Chemotherapy: The most frequently used chemotherapy regimens for germ cell tumors are: • BEP – Bleomycin, Etoposide, Cisplatin • VBP – Vinblastin, Bleomycin, Cisplatin • VAC – Vincristine, Actinomycin, Cyclophosphamide Results suggest that patients with advanced stage, incompletely resected dysgerminoma have an excellent prognosis when treated with cisplatin based combination chemotherapy. The best regimen is 4 cycles of BEP.

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